27 November 2025
Credit: JolygonBy Claudia Tanner
Neuroscientists have identified four critical ages in the average human life when the brain's structural organisation fundamentally shifts.
This occurs around ages nine, 32, 66, and 83, according to the groundbreaking study by the University of Cambridge which suggests adolescence lasts into our 30s.
The research, published in Nature Communications, analysed diffusion imaging data from over 4,200 individuals aged from birth to 90 years old. Researchers were able to map how the complex patterns of neural connections – known as topology – change throughout life.
The brain is constantly changing as we acquire new knowledge and experiences – but this research reveals the process is far from a steady, linear progression across our lifetime.
Instead, these are the five brain phases or epochs: