Game-changing weight-loss pill on the NHS a step closer after trial success

17 September 2025

Credit: Deepak Verma

By Ella Pickover, PA, and Claudia Tanner

A once-daily obesity pill has been shown in a landmark trial to help patients lose up to a fifth of their body weight, paving the way for it to be prescribed on the NHS.

One in five people taking orforglipron shed 20% over 18 months, potentially revolutionising access to treatment for millions struggling with their weight.







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